Most hydrocodone formulations include a second analgesic, such as paracetamol (acetaminophen) or ibuprofen. Examples of hydrocodone combinations include Norco, Vicodin, Vicoprofen and Riboxen. Hydrocodone/Acetaminophen is a prescription medication used to treat Moderate to Severe Pain. Learn about side effects, dosages, drug interactions, and more. Norco and Vicodin are prescription medications composed of hydrocodone and acetaminophen, a non-opioid pain reliever, in different dosage forms. Although commonly known by their brand names, they are now only prescribed as generic versions. Hydrocodone and acetaminophen is a Schedule II controlled substance. All branded hydrocodone and acetaminophen (Norco, Vicodin, Lortab, Hycet, Lorcet, Verdrocet, Xodol, Zamicet) have been discontinued, but generic hydrocodone and acetaminophen tablets and oral solution is still available. Hydrocodone and acetaminophen combination is used to relieve pain severe enough to require opioid treatment and when other pain medicines did not work well enough or cannot be tolerated. Hydrocodone/acetaminophen is a narcotic drug used as a pain reliever to treat moderate to moderately severe pain and cough suppressant. Side effects include lightheadedness, dizziness, sedation, nausea, and vomiting. Hydrocodone/acetaminophen is used to treat moderate to moderately severe pain in children older than 2 years of age, including postoperative pain. For pediatric use, this medication is dosed by weight, although there is emerging data that it may be better to dose by body surface area. Find patient medical information for Hydrocodone/Acetaminophen (Norco, Vicodin, others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Learn about Norco (hydrocodone / acetaminophen) usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. Hydrocodone Acetaminophen 5-325 is a widely prescribed painkiller, combining an opioid and a non-opioid analgesic. While effective for managing moderate to severe pain, its potential for misuse, dependence, and addiction raises significant concerns.